THE ERK MAPK PATHWAY REGULATES LONGEVITY THROUGH SKN-1 AND INSULIN-LIKE SIGNALING IN C. elegans
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چکیده
THE ERK MAPK PATHWAY REGULATES LONGEVITY THROUGH SKN-1 AND INSULIN-LIKE SIGNALING IN C. elegans Tetsuya Okuyama, Hideki Inoue, Sadatsugu Ookuma, Takayuki Satoh, Kei Kano, Sakiko Honjoh, Naoki Hisamoto, Kunihiro Matsumoto, and Eisuke Nishida From Department of Cell and Developmental Biology, Graduate School of Biostudies, Kyoto University, Sakyo-ku, Kyoto, 606-8502, Japan, and Department of Molecular Biology, Graduate School of Science, Institute for Advanced Research, Nagoya University, Chikusa-ku, Nagoya 464-8602, Japan Running head: Life span extension by ERK signaling Address correspondence to: Eisuke Nishida, Sakyo-ku, Kyoto 606-8502, Japan. TEL: +81-75-753-4230; Fax: +81-75-753-4235; E-mail: [email protected]
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تاریخ انتشار 2010